| Prognosis | Benefit 1 | Benefit 2 | ||
|---|---|---|---|---|
| 5 yr CVD risk (non-fatal and fatal) | CVD events prevented per 100 treated for 5 yrs** | NNT for 5 years** | ||
| > 30% | > 10 per 100 | < 10 | Suggested starting point for discussion with patient about drug treatment | |
| 25-30% | 9 per 100 | 11 | ||
| 20-25% | 7.5 per 100 | 13 | ||
| 15-20% | 6 per 100 | 16 | ||
| 10-15% | 4 per 100 | 25 | << | |
| 5-10% | 2.5 per 100 | 40 | ||
| 2.5-5% | 1.25 per 100 | 80 | ||
| <2.5% | < 0.8 per 100 | > 120 |
| * | cells with this marker indicate that in patients with very high levels of cholesterol (> about 8.5-9 mmol/L) or blood pressure (> about 170 / 100 mmHg), the risk equations may underestimate the true risk. Therefore it is recommended that treatment be considered at lower absolute CVD risks than in other patients. |
| ** | assumes BP reduction of about 12 / 6 mmHg in patients with BP > 140-150 / 90, or cholesterol reduction of about 20% in patients with total cholesterol > 5.0-5.5 mmol/L, produces an approximate 30% reduction in CVD risk, whatever the pre-treatment absolute risk. |