Citation: NHS Centre for reviews and dissemination. Cholesterol and coronary heart disease: screening and treatment. Effective health care 1998;4(1):1-16
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NNT for 5 yrs by annual percent risk of coronary heart disease (CER) |
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Treatment |
Relative Risk Reduction |
0.1% |
0.5% |
1.5% |
3% |
4% |
6% |
|
|
Primary Prevention smoking advice
nicotine replacement
aspirin
antihypertensive drugs <60 yrs 60+ yrs
statins |
0.01 (0 to 0.02
0.02 (0.01 to 0.02)
0.02 (-0.18 to 0.22)
0.21 (0.13 to 0.29) 0.20 (0.12 to 0.36)
0.32 (0 to 0.54) |
20000
10000
10000
950 800
625 |
4000
2000
2000
190 160
125 |
1333
667
667
63 53
41 |
666
333
333
31 26
21 |
500
250
250
24 20
16 |
333
166
166
16 13
10 |
|
|
Secondary Prevention
aspirin
beta-blockers
statins
smoking advice
oily fish
Mediterranean diet |
0.18 (0.12 to 0.24)
0.22 (0.13 to 0.29)
0.26 (0.17 to 0.34)
0.32 (0.21 to 0.43)
0.35 (0.1 to 0.5)
0.76 (0.2 to 0.8) |
|
222
181
154
125
114
52
|
74
61
51
42
38
17 |
37
30
26
21
19
9 |
28
23
19
16
14
7 |
18
15
13
10
9
4 |
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CAT Editor's comment: see also New Zealand guidelines on absolute risk of, and NNTs to prevent, CVD events
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