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The CATbank

The CATbank is presented as an example of how we can assemble an easy-to-use collection of documents which answer our questions about clinical practice. Note that these documents are not regularly updated, so you should check for new evidence before relying on their conclusions.

All CATs, listed alphabetically by disorder.
1

ALCOHOLIC HEPATITIS: Glucocorticoids may be ineffective

2

ALCOHOLIC LIVER DISEASE benefits from PTU

3

ALZHEIMER DISEASE: Support for caregivers delayed time to nursing home placement.

4

ANAEMIA: Diagnosis of underlying cause in the elderly

5

ANAEMIA: Ferritin can diagnose iron deficiency in the elderly

6

ANGINA, UNSTABLE: LMWH reduces recurrence, death, MI and need for revascularisation.

7

ANGINA, STABLE: effects of surgery.

8

ANTICOAGULATION: acetaminophen and other risk factors cause supratherapeutic INR levels in patients on warfarin.

9

ANTICOAGULATION: guidelines and consultation reduce bleeds and venous thromboembolism.

10

ASCITES: albumin prevents postparacentesis circulatory dysfunction in cirrhotics.

11

ASCITES, TENSE benefits from large volume paracentesis.

12

ASTHMA: peak flow triggered stepped care reduces revisist to A & E.

13

ATRIAL FIBRILLATION: optimal therapy for conversion of recent onset AF.

14

ATRIAL FIBRILLATION: non-valvular and stroke.

15

ATRIAL FIBRILLATION: warfarin prevents strokes.

16

BACTERIURIA: (in asymptomatic elderly women) probably doesn't benefit from treatment.

17

CAROTID STENOSIS: Carotid stenosis (symptomatic, high grade) benefits from endarterectomy (NASCET).

18

CHRONIC AIRFLOW LIMITATION: exacerbations (of dyspnoea, cough and sputom) benefit from antibiotics.

19

CHRONIC AIRFLOW LIMITATION: benefits from smoking cessation.

20

CHRONIC AIRFLOW LIMITATION: exacerbations may respond to steroids.

21

CHRONIC HEART FAILURE: Beta blockade decreases mortality.

22

CHRONIC HEART FAILURE: In heart failure patients in normal sinus rhythm, digoxin decreases hospital admissions but not mortality.

23

CO POISONING: doesn't benefit from hyperbaric oxygen (HBO)

24

DELIRIUM: doubles the death rate for patients over 65 yrs.

25

DIABETES: Diabetics can inject their insulin through a single layer of clothing.

26

DIABETIC KETOACIDOSIS: DKA doesn't benefit from NaHCO3

27

EDUCATION: Didactic educational sessions didn't improve clinicians' performance.

28

EDUCATION: Problem-based learning graduates are more up to date 15 years later (in managing hypertension) than graduates of traditional medical schools.

29

GASTROSTOMY (PEG) is safe and efficacious in neurological dysphagia.

30

GERIATRIC ASSESSMENT: improves functional status and decreases nursing home admissions

31

GUILLAIN-BARRE SYNDROME: IV immunoglobulin as effective as plasma exchange

32

HEART FAILURE benefits from angiotensin-converting enzyme (ACE) inhibitors

33

HYPERTENSION: (systolic, elderly) diuretics and beta blockers decrease strokes.

34

MENINGITIS: Head jolting and CSF pleocytosis

35

MI / angina: NNTs for alternative treatments for prevention of coronary artery disease.

36

MI and AP: Cholesterol reduction reduces morbidity and mortality (4-S study)

37

MI: Antiplatelet agents reduce the risk of death

38

MI: Reduction of average cholesterol levels decreases risk of repeat MI and death.

39

MI: IV beta-blocker can reduce vascular mortality but has side effects (ISIS-1)

40

MI: Beta blockade after myocardial infarction decreases mortality

41

MI: MIs with hyperglycaemia benefit from intensive insulin therapy.

42

MI: PTCA saves more lives (at 6 weeks) than thrombolysis.

43

MI: Streptokinase and ASA save lives (ISIS-2)

44

MI / STROKE: clopidrogel decreases ischaemic stroke, MI, vascular death compared to aspirin.

45

MI: survival improved by stopping smoking

46

MI - Cost effectiveness of tPA vs streptokinase in acute MI

47

MS - Beta interferon slows progression and reduces relapses in relapsing MS

48

PARACETAMOL OVERDOSE: Paracetamol overdose with liver failure benefits from n-acetylcysteine.

49

PULMONARY EMBOLISM: isn't well diagnosed with arterial blood gases.

50

SEPTIC SHOCK: doesn't benefit from steroids.

51

STROKE: Evaluation and early treatment in Edinburgh.

52

STROKE, ISCHAEMIC: Aspirin decreases death and recurrent stroke.

53

STROKE: risk of seizure.

54

THYROTOXICOSIS: symptoms relieved by diltiazem.

55

TRICYCLIC OVERDOSE: the QRS duration on the first limb-lead ECG can SnNout seizures and ventricular arrhythmias.

56

VENOUS THROMBOEMBOLISM: DVT: clinical exam and ultrasound can guide diagnosis and therapy.

57

VENOUS THROMBOEMBOLISM: Permanent oral anticoagulation reduces recurrent thromboembolism.

58

VENOUS THROMBOEMBOLISM: Low molecular weight heparin produces both fewer recurrences and fewer bleeds than unfractionated heparin.

59

VENOUS THROMBOEMBOLISM: warfarin may decrease the risk of recurrence in pts with calf DVT.

60

VENOUS THROMBOEMBOLISM: compression stockings reduced post-thrombotic syndrome.

61

VENOUS THROMBOEMBOLISM: in suspected DVT, 2 compression ultrasounds (1 week apart) are safe.

62

VENOUS THROMBOEMBOLISM: risk of recurrence.

63

VENOUS THROMBOEMBOLISM: pulmonary embolism: LMWH as effective as unfractionated heparin.


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